I also have the Razer Naga 2014.
It's comfortable and easy to use once you get used to it, and my hand doesn't get sore even after hours of gaming. If anything, it would be my left hand which is on my keyboard that gets sore first.
It's roughly $80. $80 that I don't regret spending.
The 12 buttons on the side are very easy to use, but I don't click them by accident. (I did once in a while the first few days, but I got used to it.)
I use the two buttons on the top to switch profiles between Minecraft, League of Legends, and what I call, "Standard," for default settings on the extra buttons, such as 1-12 instead of my customizations.
The scroll wheel is great. Not too tough to turn, and not super easy either. It does click every individual time it rotates a notch, but scrolling rapidly is not an issue.
Razer Synapse is the program that Razer provides in order to customize, create, and change macros, key mappings, sensitivity, and a whole lot of other things like the lighting on the mouse. It's very convenient and easy to use, and you can change between "profiles," or mouse settings, with a single button if you set it to do so, and if you don't then you can still do it very quickly from the application itself.
Concerning the size, my hand is probably medium-small, maybe a medium at best, and it fits me fine, maybe a bit large, but I've made it work easily.
It only took me a few days to adjust to the new mouse size, shape, and button layout.
If you're worried about getting used to learning the 12 buttons, fear not. It's a lot easier than it looks, but for 4-9 you might have to think for a split second before pressing it, until you get completely used to it, which is taking me some time. But nevertheless, I'm able to easily find any button on the whole mouse easily, and the side buttons especially are angled differently in order to distinguish themselves.